Another health care giant Moderna now joins Pfizer to begin the trial of its Omicron-specific COVID-19 vaccine. This vaccine shot development is a result of its original two-dose shots that didn’t fully protect against the Omicron virus. The vaccine in the trial is the new mRNA-1273.529 product.
The Omicron variant of the Coronavirus is an advanced mutation of the present COVID-19 virus spreading globally. It has been able to block the antibodies the human body produced as a result of the first two doses.
Research has shown the third shot, usually called the booster has been able to neutralise the virus but only for six months. Hence the need for a fourth shot which hopefully will completely neutralise the threat.
Moderna will be testing 300 people in two distinct groups. The first group of people will be those who have received a two-dose series of the original vaccine. While the second group will include individuals who had a two-dose series and a booster shot.
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Altogether, 600 people will be trialling the Omicron-specific COVID-19 vaccine of Moderna. Moderna’s vaccine has been the most effective against the coronavirus and it is highly sought after.
This sometimes has led to some shortages across different countries, due to its high demand. Moderna is optimistic this new vaccine would work. In a statement, it says its “mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and auto-immune diseases.”
This trial would be conducted across 24 sites in the United States; and it would evaluate the immunogenicity, safety, and reactogenicity of the mRNA-1273.529 vaccine.
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